@cryptonfused,The Sickle-cell disease can be inherited condition which causes pain and damage to organs and muscles, having flattened, people with the disease have stiff, round red blood cells, sickle-shaped cells.pointy blood cells get caught in the capillaries, where they block blood flow. Muscle and organ cells don’t get enough oxygen and nutrients, and they begin to die.The disease has a recessive pattern of inheritance: only individuals with two copies of the sickle-cell allele have the disease. People with just one copy are healthy.