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Migraine Sufferers - There's Good News just around the Corner!!
7 years ago in #steemstem by holbein81 (58)
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Coming from a long time migraine sufferer (including today)
who has tried each class of preventive medications and abortive medications, it's a rough road. My first question is, what side effects will these bring? I try to tough it out when possible, but I live a life interupted. Thanks for the news.
I haven't looked into the side effect profile of these drugs, but no doubt there will be some...
Clearly the developers think the risk-benefit profile is positive, hence the submission to the regulatory authorities. I guess we will see if the authorities agree...
I hope you manage to find something that works for you!
Cheers
Thank you. I am always seeking new forms of treatment. Take care!
@wandrnrose7 have you ever tried dietary modifications, acupuncture or supplements under professional advise? They should be able to at least decrease the frequency of your migraines without negative side effects.
I've tried supplements, PT, and am using cranial chiropractic currently. Acupuncture is pricy and not covered. I appreciate your suggestions and hopefully winter will come with relief.
Which supplements?
Goldenseal and magnesium so far.
Magnesium comes in a variety of forms which all have different rates of absorption and is mostly symptomatic in nature for treatment to help open up blood vessels and reduce platelet stickiness.
Goldenseal I see mostly as antimicrobial herb with gut regulating activity. Not my first choice for migraines. So you haven't exhausted your non-pharmaceutical options by any means.
Food is really important just wanted to re-emphasis that.
Thank you, what are the best supplements for migraine sufferers?
I'd be willing to explore them since my physician now recommends just Botox.
Very informative post indeed buddy. Loved it.
Regards Nainaz
#thealliance
Thanks for swinging by Nainaz!
A very interesting read ,my Wife has had headaches for months and nothing has fixed it yet but am hoping for something to take them away soon
I dont know if it is Migraines she has or not Drs haven’t confirmed yet but is good to read about new options for treatment
Hope she manages to get it sorted!
Thanks for commenting!
My pleasure to visit
And I hope so as well
Nice informative post.
However, you got the drug mechanism wrong. Both erenumab and fremanezumab are antibodies. They are not reducing CRGP levels, but are binding to the protein and therefore reduce it's capability to interact with its natural ligand. I.e., they partially inactivate it.
and:
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Ok, fair point - but the point of this article was not to explain the MoA of these compounds, that would be a whole post in itself, and is why I glosssed over it in less than a paragraph
Cheers
My question is why only settle for a 50% reduction. Why not change your diet so you are not eating your proinflammatory trigger foods and cut your migraine frequency even more.
That drug is not fixing the reason you are getting the migraine.
If people knew with 100% reliability what was going to cause every migraine and were able to avoid these triggers with 100% reliability then there would be little need for medication
Unfortunately that is not the case
Unfortunately people aren't searching for the cause they are looking for a quick fix and calling that treatment.
Food comes with a lot of emotional triggers. Some people will continue to try to eat the foods that they know will cause a migraine if they are stressed and need some comfort that they aren't receiving elsewhere in life.
I think everyone can agree that preventing the cause would be ideal - if there was a way that effectively worked in all people. Maybe one way day that will be discovered
Until then, as with so many diseases, incremental progress is being made - these developments are a significant (scientifically speaking) step forward. They won't work for everyone, but clearly they will help a lot of people
I don't think anyone can realistically believe that the process of taking a drug through development and onto the market is a 'quick fix'
I meant a quick fix in relation to the effort that the person puts into healing themselves. There is nothing easier then just taking a pill compared to making diet and lifestyle changes which require habit changes.
The problem with western medicine is that it treats everyone the same and assumes that there is one cause for getting a certain illness which most definitely is false. There is no one way to a cure for a migraine but their is the way that works for you as a individual.
If you habitually just cover up symptoms you will keep going towards chronic disease which is the norm in our society today because we always want to just cover up symptoms.
Ah sorry I misunderstood you.
I certainly agree that each individual is responsible for their own health! It’s just a shame that nobody has told them....
And I agree it is true that Western medicine, or pharmaceuticals, has been looking for medicines to be used on all patients with a specific condition, irrespective of next level genotype/phenotype.
The good news, maybe, is that this approach does seem to be evolving - but no doubt there is a way to go
Cheers
This post has received gratitude of 1.98 % from @appreciator thanks to: @holbein81.
Interesting post! Thank you for sharing!
Being a chronic migraine sufferer, I would say that botox injection around the head and shoulder works for me best. However the effects lasted me for 4.5 months.
I still remember that after the injections, the skin and muscle around my head and shoulder tightens and the pain and giddiness were gone. I was very happy and my wife said that she has not seen me so active and happy for such a long time.
However once the effects subsided, things turned for the worse and I had to be hospitalised and go on a IV drip treatment to halt the migraine pains.
The botox treatment is very expensive for my pay grade so I did not continue such treatment anymore. But I would imagine if anyone can afford it long-term, the treatment will really let you carry on your life normally.
As for myself, I currently still suffers from migraine and each time it lasts on average, 2 weeks. I am no longer on any long-term medication (the withdrawal syndrome from cutting away SSNRI drugs were very nasty!) and I simply manage my activities carefully and take as much rest as possible when needed.