Typically, I vote for witnesses that support manual curation of quality content and less favorable towards paid voting / delegation schemes. I also place a significant emphasis on abuse fighters and not voting for those who I have identified as having collusive voting patterns or supporting those that do and, yes, some of these are within the top 50.
Do your homework people!
Very true! Thing is like any political system MOST won't do their homework, and that's why I suggest people who don't care to use proxies