CRISPR kills HIV and eats Zika 'like Pac-man'. Its next target? Cancer

in #science7 years ago

Researchers paired proteins with a process that amplifies RNA which could be used to detect cancer cells

There’s a biological revolution underway and its name is CRISPR.

Pronounced 'crisper', the technique stands for Clustered Regularly Interspaced Short Palindromic Repeat and refers to the way short, repeated DNA sequences in the genomes of bacteria and other microorganisms are organised.

Inspired by how these organisms defend themselves from viral attacks by stealing strips of an invading virus’ DNA, the technique splices in an enzyme called Cas creating newly-formed sequences known as CRISPR. In bacteria, this causes RNA to make copies of these sequences, which help recognise virus DNA and prevent future invasions.

This technique was transformed into a gene-editing tool in 2012 and was named Science magazine’s 2015 Breakthrough of the Year. While it's not the first DNA-editing tool, it has piqued the interest of many scientists, research and health groups because of its accuracy, relative affordability and far-reaching uses. The latest? Eradicating HIV.

Read more!
https://www.wired.co.uk/article/crispr-disease-rna-hiv