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your brain is a body part. I think what you mean is that you are unlikely to die as a direct result of an overdose , but you know as well as I do people have hopped out of windows and crashed cars and done other things as a result of LSD, or become depressed or anxious for long periods after bad trips. People can and do die from overdoses of caffeine and especially aspirin, but it does not make people think they can fly. those are all legitimate dangers.