You can always take a couple shots of the same composition and make little micro adjustments with your focus; that way, you have a few to choose from in case your single shot isn't focused correctly. Always good to have more than you need!

I also have a Canon 6D, awesome camera! I do a lot of filmmaking, and I always shoot more than I need. A lot of times, I find that I'm glad I kept the camera on for a few seconds longer, or shot more of the same composition. Because when you get back to your computer, things look much different than they did on your camera screen!