In Carl Sagan's words, "there is no refuge from change in the cosmos".
The reason we resist change is evolutionary. One could say that life itself is nature's resistance to randomness. Evolutionary speaking, if something works you don't change it. If you end up in a place with food and shelter, you don't risk losing it without a good reason. Taking chances could mean trouble, danger, and energy loss. This is why we have become lazy in regards to changing what we are comfortable with. Nowdays "change" refers to mostly ideological adaptation than physical movement. It takes mental effort to do so but it surely pays back.