Serotonergic System
Serotonin Agonists
Tryptamine
Indole Alkaloid
Lysergic Acid

Tryptamine
Strychnine
Scopolamine
Atropine

Serotonin Agonists
Receptors
5-HT / 5-HT2A

Tryptophan is the biogenetic precursor for most indole alkaloids, with decarboxylation often forming tryptamine.

Tryptamine synthesis involves building its core indole ring with an ethylamine side chain.

Attaching the aminoethyl group via nitrile reduction, amide conversion, or direct alkylation, leading to various natural/synthetic psychoactive compounds like DMT, psilocybin, serotonin, and drugs like sumatriptan.

tryptamine and many related compounds, are known to have a very bitter taste.