For sure!
Pretty much my biggest pet hate is a load of comments on a post, without a single response.
Greed, laziness, and a bunch of other things are the negative reasons.
If you have a large account, you might be able to get away with this, but it's still gonna look shit for you.
I've had words with a few people, mainly because they are discussing engagement, or shilling themselves to be awesome for Steemit, and yet doing 0 of that they speak of in their blogs.
As a small account, it is essential to get through as many replies as possible / that are worthy of a response. This is where you will pick up and keep followers.
Cheers!