Remote working could be seen as a great thing; however, if we question it, it might have some real negative effects. I have been working mostly remotely for two years. Here are what I have experinced in negative:
You might lose organizational or working culture
You might work with less breaks than in office
You might get used to be lazy
You might lose being a social creature then have some psychological problems
I have experienced the same, except the laziness - though when I do have lazy days, it is very easy to do less than an in office lazy day :)