While Zuckerberg’s opening comment was just a friendly jab at Huang, it set the tone for Zuckerberg’s new attitude toward life and business. The founder of Facebook has spent a lot of time apologizing for Facebook’s content moderation issues. But when reflecting on the biggest mistakes of his career, Zuckerberg said his largest one was a “political miscalculation” that he described as a “20-year mistake.” Specifically, he said, he’d taken too much ownership for problems allegedly out of Facebook’s control.