Some notable examples of colonial architecture in Santo Domingo include:

1. Cathedral of Santa María la Menor: A 16th-century cathedral that was built on the site of an earlier church. The cathedral features a mix of Gothic and Renaissance styles.
2. Convent of San Francisco: A 16th-century convent that was built by the Franciscan Order. The convent features a mix of Gothic and Renaissance styles.
3. Fortaleza Ozama: A 16th-century fort that was built to protect the city from pirate attacks. The fort features a mix of Gothic and Renaissance styles.