So while neuroscientists struggle to understand how there can be such a thing as a first-person reality, quantum physicists have to grapple with the mystery of how there can be anything but a first-person reality. In short, all roads lead back to the observer. And that’s where you can find Hoffman—straddling the boundaries, attempting a mathematical model of the observer, trying to get at the reality behind the illusion. Quanta Magazine caught up with him to find out more.