"Oppenheimer" received widespread critical acclaim, with many praising Murphy's performance and Nolan's direction. The film holds a 92% approval rating on Rotten Tomatoes, with an average rating of 8.4/10.

At the box office, "Oppenheimer" performed well, but not spectacularly. In the United States, the film grossed $95.4 million, which is a respectable but not outstanding total for a film with a budget of around $100 million. Globally, the film grossed $215.4 million, which is a decent total but not as high as some of Nolan's other films.