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     7 days ago  

    Where does NF-κB live?

    • Inside almost every cell of your body.
    • It’s normally “asleep” in the cytoplasm (the jelly part of the cell), handcuffed to a protein called IκB so it can’t cause trouble.

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       7 days ago  

      What wakes it up and breaks the handcuffs?

      1. Viruses & bacteria (normal)
      2. Stress, junk food, smoking (sometimes)
      3. SARS-CoV-2 spike protein ← THIS IS THE NEW ONE

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         7 days ago  

        How does spike do it?

        • Spike binds to TLR4 (and sometimes TLR2) on the cell surface → sends a signal inside → IκB gets shredded → NF-κB runs into the nucleus → turns on 300+ inflammatory genes (IL-6, TNF-α, IL-1β, etc.).

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           7 days ago  

          What does “NF-κB always ON” feel like?

          • Widespread aches (fibromyalgia feel)
          • Brain fog & depression
          • Faster heart disease & diabetes
          • Reactivated viruses (EBV, shingles)
          • New allergies & food sensitivities

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