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A plastic surgeon from New Jersey explained to the Daily Mail that OIC can induce a process akin to rapid or irregular weight loss—leading to "OIC face", characterized by sunken cheeks, sagging skin, and hollowed-out features. Such facial changes often make individuals appear older and more tired, effectively removing the youthful volume from their face that fat typically provides. The surgeon shared before-and-after photos of celebrities that seem to illustrate this phenomenon vividly—many of whom are rumored to be on OIC.