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Evolutionary Scale's AI Breakthrough: Designing New Proteins from Scratch
Evolutionary Scale: Shaking Up Biology with AI
Evolutionary Scale is an AI research lab that has made waves in the world of biology. Founded in 2023, their ambitious goal is to make biology "programmable" using AI. This team has serious credentials, having developed ESM1, one of the early protein language models, while at Meta (Facebook).
ESM3: A Protein Encyclopedia on Steroids
The centerpiece of Evolutionary Scale's work is their AI model, ESM3. This generative AI was trained on a staggering 2.78 billion proteins, giving it an encyclopedic knowledge of protein sequences, structures, and functions. Unlike other protein-focused AI models, ESM3 looks beyond just the sequence, also considering the 3D structure and function of proteins.
The GFP Breakthrough: Creating New Proteins from Scratch
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