It is a world of sacrifice.
This topic reminds me of my all time favorite manga Berserk. It is about a man with a great ambition. To achieve his goal he had to sacrifice everything he had.
At some point sacrifice becomes not worth it- we lose as much(or more) than we gain.
I think that a lot of big achievers sacrifice what others are unwilling to give up. Many are unwilling to give up much at all.
But, where is that "not worth it" point? It can be hard to find, especially while achieving goals.