If the job is for a skilled position and the resume or cv you presented hits all the right qualifications and the interview goes well, you get the job.
Have you ever been (and or have you ever spoken to someone who has been) rejected for being "overqualified" for a job ?
Na, but I've heard of it happening, it should be the goal of any good HR person to place the position correctly the first time. If you don't, and it's a trained position, then they'll have to retrain someone else. I think they try and weed out would be malcontents before they have the opportunity to become disappointed.