Yes, you'll be able to subscribe to as many mute lists as you want. It works just like following blacklists.

When a user logs into hive.blog, the UI will prompt them to make choices about blacklists and mute lists they want to use. If they don't want to use any of them, they can follow the null account's lists (we plan to use that to avoid prompting them again).

Each condenser instance will be configurable, so that the host's operator can make suggestions about which lists a user may want to follow. For hive.blog, we will have the irredeemables as one of the choices for a mute list to follow.

List following is a hivemind-level feature, so list following effects apply across all front ends.