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I know. Read the article. Thing is I don't think any of these substances offer substantial "power up". Most of not all, act much like a placebo.

Id beg to differ, many of the OTC nootropics may rather minute in power, but as someone who has been apart of the community since places like silkroad were the only places one could find these, there are many more that are far from "placebo" . You should look into biohacking though, nootropics is just one of the subcategories of the biohacking-sphere.
http://forum.biohack.me/

I am aware of their existence but haven't found any evidence for their efficacy. In theory they do work. in practice, no.

Actually the do, even caffeine works but it suffers from the same downsides that everything else does, which is tolerance.

3meo-2xox-pce definitely works for what I used it for. It had one major downside though and that was the mania that accompanied it even while microdosing. Then there are different forms of magnesium that are more soluble than others. And there are also pure neuropeptides now, which is really the way that the industry is shifting. Rather than taking drugs that effects my brain a certin way to produce the release of neurotransmitter, why not just go to the source and directly take the neurotransmitter

i like magnesium and just got some! But while it can be considered a nootropic...for me is still in the "safe" zone: caffeine, l-theanine, magnesium threonate...
what do you think of it?

I have a friend who works for one of the bigger nootropics companies and the only thing that he currently takes on a daily basis is magnesium threonate. Don't quote me on what it does exactly, but I'm pretty sure that magnesium helps protect your brain from everything else. We produce it naturally, but if you're increasing the levels of other chemicals artificially than you also need to increase the level of magnesium

if you read Tim Ferriss's last book [ which i recommend ] "tools of titans", many, many people talk about the need to take magnesium daily.
I'll see how I feel and order more!
thanks a lot

how many of these nootropics have you tried? EDIT @kyriacos

None. Personal experience is irrelevant

you're saying that none of them work, yet you've tried none of them, and that personal experience Is irrelevant... personal experience is always relevant, and should always be even more relevant to you(the person experiencing) than anything else. Who gives a fuck if every college in the world agrees that substance D is not the cause of symptom F. Until somebody who refuses to believe that the current scientific consensus is correct brings their own personal experience to lite, nothing changes and nobody even begins to look deeper in that direction

You're making a huge sweeping statement criticizing our science, and providing nothing but conjecture to back up this criticism... Even a personal account would be more relevant to a 3rd party observer than what you're currently telling us.

@kyriacos lol oke. I'm gonna go talk to that tree over there. waving hand