New investigation provides intriguing clues about the relationship between fever during pregnancy and babies born with autism.
A recent study led by scientists at the Center of Investigation and Immunity (CII) at Columbia University Mailman School of Public Health in New York, demonstrated that fever is a detonant for Autism Spectrum Disorder (ASD). Dr. Mandy Hornig, lead researcher on the study, said that fever (a common condition during pregnancy) is how the body responds to a wide range of infections.
The extensive study, published June 13th in the journal Molecular Psychiatry, also found that even one episode of high fever during the second trimester might increase chances of autism by 40%. Women who suffered three or more fevers after 12 weeks of gestation increase this chance threefold.
Hornig warned that this only proves that there is a connection between fever and higher risks of developing ASD. Yet, there’s not enough evidence to prove that this symptom directly causes autism. There might be other conditions that could predispose the infant to develop autism.
She also added that the fever effect could be related to an infection, which could trigger the bodily response. “There is something in the mother’s immune response that may increase the risk for the infant, but it’s not in every mother” Hornig said. “We don’t think this is a pathway for autism. We don’t think it’s the only way autism is triggered in children”.
Hornig and colleagues collected data from 95,754 Norwegian children born from 1999 to 2009. Among these, 15,700 were born to mothers who experienced at least one fever during their pregnancies. From these kids, 583 were diagnosed with autism spectrum disorder.
Researchers also focused on the medications mothers took to treat fever episodes. Surprisingly, acetaminophen (Tylenol) — the most common drug used to reduce fever — had no significant impact. Mothers who took Ibuprofen didn’t report any cases of autism in their infants. Still, there’s not enough evidence to support this theory.
Hornig also pointed out that additional research is necessary to identify the mechanism and correctly understand how inflammation relates to autism spectrum disorder.
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Very interesting. Now I think they should look further into how the medicine mothers take might come to play when predicting autism, and also if specific genetic traits affect this probability.
Keep us updated then!
mine refused to take any medicine, and refused to drink coffee.
Maybe this will quench some of the more stupid anti-vaxxer campaigns to ban vaccination. I doubt it, but you never know.
Obviously, since vaccinations can cause fever, and other flu-like symptoms in general, along with the specific symptoms of the disease being vaccinated against, autism COULD be triggered as the result of a pregnant mother's vaccination. The same response to fever COULD be triggered after birth in a baby, this would certainly be worthwhile data research.
There WOULD be a statistical incidence of autism triggered strictly by vaccines- it's worthwhile simply plugging the data into a risk analysis.
Love it. I love blaming things on vaccines, I read that vaccines are the reason we are so sarcastic as a society.
Since autism generally is a mutation in the SHANK3 gene (or in the case of Asperger's multiple copies of a normal SHANK3 gene) , it seems strange that any fever would cause this one specific genetic change. Schizophrenia is also linked to the SHANK3 gene, and both autism and schizophrenia are more prevalent with older fathers. Maybe the fever could have something developmentally with unlocking it at clinical levels-but I doubt the cause. I say it is a condition that is unlocked because men are 3 times more likely to have it than women, and women tend to be more social. Also with Older fathers, it is less likely that the father will be in the same social circles as his kids peers' parents as would be the case of younger parents-likewise there would be a difference in interest between the generational or even half generational gap.
For people in my generation, it is likely brought on by being constantly bullied from others-often in the form of latent antisemitism. There are those who advance, myself included, that so far as asperger's is concerned, it more closely followed social rejection theory than autism. Mine is definitely an adolescent onset. Autism's increased prevalence over recent years I suspect is probably due to more kids becoming fixated on video games than in past generations which contributes to further social isolation, and unlocking the condition to clinically identifiable levels. And with kids becoming fixed on iphones, etc, at the further detriment of their social skills, it will probably continue to rise. Perhaps it may even spread to those who don't have either multiple copies of SHANK3 or the mutation of the SHANK3.
Stop letting the iphone or playstation babysit your kids. Get them out to play games, study, etc, with other kids their age.
I love the progression of you post, I have hear your head shacking "damn video games". I don't mean to poke fun, I love it.
When I read articles like this I keep thinking we need more data. We can learn "The Truth" of everything , we just need more data.
Exactly, but it needs to be objective and untampered. Studies (that lead to data) are usually paid by Lobbies with certain interestests. So maybe we need a decentral voting system on what to study and therefore which study to fund.
Preach on!!! I will come back later to tell you about an idea to solve health using the blockchain.