I think anxiety issues can be relieved, there was an application process so he could make sure the ceremony and substance would be right for each individual, because there are certain mental health issues that can pose problems when taking the substances.
I stayed at a sanctuary in the Amazon rainforest for about a week, we had 3 ceremonies with Huachuma, which I think is mescaline based. There was Ayahuasca the week before, which I missed. At the end of the third ceremony we used Vilca as well. Basically these medicines work within us to relieve some of the issues we've built up. Ayahuasca is supposed to be quite healing, but can be very uncomfortable during for some people. It is taken in a dim lit room, while Huachuma is quite gentle, we were out interacting with different tribes and doing things. It's similar to muchrooms in some ways. MDMA I haven't tried, but it has clinical studies being done.
I'd suggest looking into it, I feel like psychedelics are some of the most healing substances available to us. Check out reset.me for more info, spiritquest sanctuary is where I went.
I've found relief from diet, exercise, and nature in a big way. They are my go-to's, though I need to improve on how much I was doing last year.
That sounds really interesting, people really need to look at these alternatives much more than the standard treatment route, have you had much luck with supplements? Vitamin D seems to be a huge one for mental health.
I personally take Vitamin D, a greens supplement(I use amazing grass,) a collagen protein, and then just take "superfood" supplements like maca, chia, matcha, etc. I'm the biggest believer in medicinal mushrooms. I've taken Lion's Mane, Reishi, & Cordyceps and always felt great on them. I'd suggest looking into Paul Stamets work on mushrooms, I truly think they have the power to save the world, really fascinating organisms