Selling all at this point would definitely be a bad move, is all it amounts to would be a loss of money. Keeping cold head, exercising patience and firmly HODLing your coins through this storm is the only strategy to avoid losing your original investment. You may or may not want to use this period to buy more coins – they all are rather cheap at the moment. I myself am using every such "crash" to increase my cryptoholdings.
And, if you still believe in this technology, if you believe in the cryptocurrency projects that you chose to invest in, if you believe in its future potential, then hold on tight to your coins through this period of price crash and panic selling.
I am still confident that we will see the price of USD $5,000/BTC in 2018. Maybe it'll go even higher, but fifty thousand seems like a realistic milestone for Bitcoin this year. Some other coins (Ether, Dash, STEEM, EOS and a few others) might enjoy even greater gains this year. 2018 is going to be amazing for crypto, despite this rough start of the year.