Although, not completely related to the technical aspect of your post- I discovered a method of roach extermination on Amazon.com -which proved to be more effective than modern pesticides. Boric acid pellets worked more effectively because the roaches will crawl upon the pellets and often ingest the powder from the pellets as well.
Aftéwards, the roaches will transport the powder from the pellets back to the nests via its limbs. All of the roaches in the nest are exposed to the Boric acid residue introduced by the host. The host dies and all of the roaches in the nest as well.
Their ability to mutate and reproduce is cancelled within the nest environment. All other roaches -when exposed to the morbidity within the nest, will eventually flee the immediate area of infestation.
I believe modern manufacturers of pesticides discovered that boric acid was less profitable-because the roaches ceased to mutate, reproduce and develop the instinct necessary to evade attack.